AARC Clinical Practice Guideline: SELECTION OF DEVICE, ADMINISTRATION OF BRONCHODILATOR, AND EVALUATION OF RESPONSE TO THERAPY IN MECHANICALLY VENTILATED PATIENTS (1999), 44, 1, 105.
www.rcjournal.com/cpgs/pdf/01.99.105.pdf


AARC Clinical Practice Guideline: SELECTION OF DEVICE, ADMINISTRATION OF BRONCHODILATOR, AND EVALUATION OF RESPONSE TO THERAPY IN MECHANICALLY VENTILATED PATIENTS (1999), 44, 1, 105.
www.rcjournal.com/cpgs/pdf/01.99.105.pdf



Ebrahim H (2010) Noradrenaline versus dopamine in the treatment of circulatory shock. J Intens Care Soc, 11, 4, 272-4
journal.ics.ac.uk/pdf/1104272.pdf
• dopamine shows slightly more adverse effects than noradrenaline

Balasubramaniam B (2003) Sexual hallucinations during and after sedation and anaesthesia.
• midazolam and propofol can cause sexual hallucinations

Behbehani NA (1999) Myopathy following mechanical ventilation for acute severe asthma. Chest, 115, 1627-31
• muscle relaxants can cause persistent myopathy if taken with steroids

Cammarano WB (1998) Acute withdrawal syndrome related to administration of analgesic and sedative medications. Crit Care Med, 26, 676-84

Cohen D (1996) Modulating effects of propofol on metabolic and cardiopulm. responses to stressful ICU procedures. Crit Care Med, 24, 612-17
• propofol reduces metabolic and haemodynamic disturbance

Cook DJ (1998) Incidence of and risk factors for ventilator-associated pneumonia. Ann Int Med, 129, 433-40
• neuromuscular blocking agents increase the risk of pneumonia

de Molina FG, Ferrer R (2011) Appropriate antibiotic dosing in severe sepsis and acute renal failure: factors to consider. Crit Care, 15, 175
ccforum.com/content/15/4/175/abstract

Dhand R (2004) New frontiers in aerosol delivery during mechanical ventilation. Resp Care, 49, 666-7
www.rcjournal.com/contents/06.04/06.04.0666.pdf
• latest devices

Dorisanne D (2003) Aerosol delivery and modern mechanical ventilation Am J Respir Crit Care Med, 168, 1205-9
ajrccm.atsjournals.org/cgi/content/full/168/10/1205
• aerosol delivery in ventilated patients must have tightly-controlled ventilator parameters

Duarte AG (2000) Bronchodilator therapy with metered-dose inhaler and spacer versus nebulizer in mechanically ventilated patients. Respir Care, 45, 817-23

Gallagher G (2000) The use of a target-controlled infusion of alfentanil to provide analgesia for burn dressing changes. Anaesthesia, 55, 1159-63
• effective pain control without sedation

Gamrin L (2000) Protein-sparing effect in skeletal muscle of growth hormone treatment. Ann Surg, 231, 577-86
www.annalsofsurgery.com/pt/re/annos/abstract.00000658-200004000-00018.htm;jsessionid=CmZBwXQIzcEwv7tJK5oJj8mQBg2G0HCG5KKQPVhuU8PZssnUTPag!-2006515172!-949856031!9001!-1?index=1&results=1&count=10&searchid=1&nav=search&database=lwwovft
• growth hormone stimulates muscle protein synthesis in critically ill people

Govindarajan R (2002) Epidural buprenorphine in management of pain in multiple rib fractures. Acta Anaesth Scand, 46, 660

Griffin S (1992) Acute myopathy during treatment of status asthmaticus with corticosteroids and steroidal muscle relaxants. Chest, 102, 510-14.

Hawryluck LA, Harvey WRC, Lemieux-Charles L, Singer PA (2002) Consensus guidelines on analgesia and sedation in dying intensive care unit patients. BMC Medical Ethics, 3, 3 www.biomedcentral.com/1472-6939/3/3

Hermans G (2009) Benefits of intensive insulin therapy on neuromuscular complications in routine daily critical care practice. Crit Care, 13, 1, R5
• intensive insulin therapy reduces critical illness polyneuropathy and/or myopathy
• risk factors for myopathies – sepsis, hyperglycaemia, vasopressors, catecholamines, neuromuscular blocking agents, corticosteroids, hypoalbuminaemia, parenteral nutrition, prolonged ICU stay

Marik P (1999) A comparison of bronchodilator therapy delivered by nebulization and MDI in mechanically ventilated patients. Chest, 115, 1653-7
• inhalers better than nebulisers

McKenzie CA, McKinnon W, Naughton DP (2005) Differentiating midazolam over-sedation from neurological damage in the intensive care unit. Crit Care, 9, R32-R36
• method to differentiate over-sedation from neurological damage

Müller S, How O-J & Hermansen E (2008) Vasopressin impairs brain, heart and kidney perfusion: an experimental study in pigs after transient myocardial ischemia. Crit Care, 12, R20
ccforum.com/content/12/1/R20/abstract

Murdoch S, Cohen A (2000) Intensive care sedation. Int Care Med, 26, 922-8

Nakos G et al (2002) Immunoparalysis in patients with severe trauma and the effect of inhaled interferon. Crit Care Med, 30, 1488-94
• interferon can strengthen immune system after trauma

Rowlee SC (1999) Monitoring neuromuscular blockade in the ICU. Heart Lung, 28, 352-62
• monitoring by peripheral nerve stimulator

Ruggiero MS (2008) Effects of vasopressin in septic shock. AACN Adv Critical Care, 19, 3, 281-7.
www.aacnclinicalissues.com/pt/re/aacn/abstract.01256961-200807000-00007.htm;jsessionid=L2ySZBJvdQB5d7PGQv2trQTTqdLDqMrsk5cRVMfCV62zKv1lr0Bh!-101412872!181195629!8091!-1
• how vasopressin helps to restore blood pressure

Shehabi Y (2010) The effect of dexmedetomidine on agitation during weaning of mechanical ventilation in critically ill patients. Anaesth Int Care, 38, 82-90
xa.yimg.com/kq/groups/16749867/2013815741/name/The+effect+of+dexmedetomidine+on+agitation+during+weaning+of+mechanical+ventilation+in+critically+ill+patients-+Anesth+Intensiv
• Dexmedetomidine achieves rapid resolution of agitation

Smalldone GC (1999) Aerosolized bronchodilators in the ICU. Am J Respir Crit Care Med, 159 1029-30
ajrccm.atsjournals.org/cgi/content/full/159/4/1029?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&searchid=1088418990960_1296&stored_search=&FIRSTINDEX=0&volume=159&firstpage=1029&journalcode=ajrccm
• a humidifier reduces nebuliser drug delivery by 40%, but should not be removed because of the time taken for disconnection and drying of the circuit. The dose should be adjusted

Smalldone GC (2004) Aerosolized antibiotics in mechanically ventilated patients. Resp Care, 49, 635-9
www.rcjournal.com/contents/06.04/06.04.0635.pdf

Smith-Blair NJ (2003) The effect of dobutamine infusion on fractional diaphragm thickening and diaphragm blood flow during fatigue. Heart Lung, 32, 111-20

Sprung CL et al (2009) Steroids in patients with septic shock. Chest, 136, 323-4

Tuon L, Comim CM, Petronilho F et al (2008) Memory-enhancing treatments reverse the impairment of inhibitory avoidance retention in sepsis-surviving rats. Crit Care, 12, R133
ukpmc.ac.uk/articles/PMC2592772/
• cognitive impairment following sepsis may be treated by modulation of the adrenergic system

Wollam PJ (1994) Prediction and assessment of bronchodilator response in mechanically ventilated patients. Respir Care, 39, 730-5.